Learn how the backup command for coupling facility structures used by MQ is clever and avoids backing up recently put messages.
You no longer need to remember which channel disposition (CHLDISP) you should use on an MQ for z/OS channel command, this post will teach you how to set up the defaults.
Learn how to use a CCDT to spread your client connections across the set of queue managers that can accept their connections, instead of all clients going to the first queue manager in the list.
Learn how to selectively use the queue manager's dead-letter queue on only some channels and topics, solving that age old problem, where one channel that can't suffer a dead-letter queue cause all channels to forego using it.
The DISPLAY QMSTATUS command on the distributed platforms provides a number of useful pieces of information about your queue manager. Read more about them, and where to find the equivalent information on a z/OS queue manager.